• About
  • Contact
  • Testimonials
  • Newsletter
  • More
    • Demographics & Advertising Rates
    • Terms & Conditions
Friday, February 3, 2023
No Result
View All Result
California Business Journal
  • Front Page
  • Business
  • Finance
  • People
  • Featured
  • Opinion
  • Technology
  • Law
  • News
  • Food
  • Art & Culture
  • Human Interest
  • Education
  • Insurance
  • Real Estate
  • Health & Fitness
California Business Journal
turaga-hipec-closeup-tier-hero-1444x434

Next Level: Hyperthermic Intraperitoneal Chemotherapy

The procedure is for washing the abdominal cavity with a heated chemotherapeutic drug of high concentration. It is carried out directly during the surgical removal of malignant tumors.

by Dale Weinbaum, California Business Journal
A A
Share on FacebookShare on Twitter

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) affects cancer cells in the abdominal cavity, as close as possible to the area where the primary tumor was located. In contrast, conventional chemotherapy circulates throughout the body.

Hyperthermic chemotherapy of the abdominal cavity allows a higher concentration of drugs to be used. Heating the solution improves the effect of chemotherapy on the tumor.

The mechanism of HIPEC action

During surgery, all visible tumors are removed, but cancer cells may still remain in the abdominal cavity. If these cells are not destroyed, they will give rise to new foci, a relapse will occur, and the entire effect of the treatment will be nullified.

HIPEC helps to solve this problem. Through catheters connected to a special apparatus, the patient’s abdominal cavity is washed with a chemotherapeutic solution heated to 42-43°C. The procedure lasts for 30-90 minutes, after which the solution is completely removed from the abdominal cavity. Healthcare professionals constantly control the flow rate, pressure, and volume of the solution.

Why is intraperitoneal chemotherapy used?

Intraperitoneal chemotherapy is a treatment option for some patients with high-risk localized or metastatic malignancies of the abdomen. The use of a neonatal PICC line can be considered in these cases to manage post-chemotherapy complications such as bowel obstruction, ileus, and venous thromboembolism. These devices are inserted through an abdominal incision and positioned towards the pelvis on either side of the bladder. After removal of chemotherapy, they may also facilitate drainage after intraperitoneal hemorrhage or perforation.

Many types of cancers arising from the abdominal organs can also affect the abdominal membrane, called the “peritoneum.” Peritoneum is a tissue that facilitates the friction of organs by secreting a small amount of fluid that covers both the inside surface of the abdominal wall and the surface of the organs.

In cancers originating from the intraperitoneal organs, the cancer cells metastasize to the peritoneum. This usually indicates that the cancer has reached its final stage. For cancers associated with the peritoneum, conventional chemotherapy is ineffective because medications cannot reach the peritoneum.

The basic principle for treating abdominal cancer is the removal of the affected peritoneum and internal organs using cytoreductive surgery. Intraperitoneal chemotherapy is carried out after this operation in order to destroy the residual metastases.

Why does heating a chemotherapeutic drug give more benefits?

The heating of chemotherapeutic drugs gives the following positive effects:

  • Heat helps to improve the penetration of drugs into tissues.
  • Heat increases the destructive effect of a chemotherapeutic agent on cancer cells.
  • Heat has an antitumor effect itself.
  • As a result of heat, the drug is distributed evenly over all surfaces within the abdomen.

In addition, during HIPEC, you can monitor how the drug affects kidney function. Many physiological parameters (body temperature, coagulation, hemodynamics, etc.) can be normalized during the procedure. Moreover, tumor cells are mechanically eliminated from the surface of the small intestine and layers of fibrin clots.

When is HIPEC performed?

This therapy is most often used to treat ovarian cancer in women. In addition, it is used for cancer of the colon, stomach, appendix and cancers of the peritoneum. In recent years, it has also been used in pancreatic cancer. Peritoneal disease often involves the accumulation of fluid (ascites) in the abdominal cavity. These causes bloating of the patient’s abdomen, as well as spreading cancer cells to the diaphragm and other intra-abdominal organs.

Usually the fluid is removed via laparocentesis, but this does not solve the problem completely. Ascites will appear again as its root cause remains. Many patients with this disease are told that doctors cannot help them. In such patients cytoreductive surgery and HIPEC are used.

ADVERTISEMENT
What are the contraindications for HIPEC?

HIPEC is not used for the therapy of metastases located outside the abdominal region. The oncological process should be localized only in the abdominal cavity. In addition, HIPEC chemotherapy is not used in patients with multiple liver metastases that cannot be removed. However, if metastases are not numerous HIPEC can be performed.

In patients with severe damage to the small intestine HIPEC is not performed. Most of these cases cannot be diagnosed before a surgery, it is possible to detect them only during the operation itself. Most candidates for this therapy are patients at the last stage of the disease, whose life expectancy is limited to several months. For them, this is the last hope for survival.

Where can I undergo the HIPEC treatment?

HIPEC procedures have been actively applied worldwide for several years. In recent years, the technology has been improved. This technology is widely used abroad, in particular in Germany, where a number of healthcare institutions have modern equipment for this procedure.

In German clinics, you can undergo diagnostics and treatment as soon as possible. You can learn more about the HIPEC surgery on the Booking Health website, having reviewed all the programs and methods of treatment abroad.

Related Posts

2
ACCELERATING THE EARLY DRUG DISCOVERY PROCESS
Why you need health insurance
How Healthcare Companies Can Meet Regulatory Compliance
medical diagnose
How To Cope When Struggling To Get A Medical Diagnosis For Your Chronic Illness
Tags: agentbenefitscancerConventionaldevicesdoctorsdrugshealthhealthcareheatingHipec surgery in cancer treatmentimproveITrisesolutiontechnologytherapytreatment
ADVERTISEMENT
Dale Weinbaum, California Business Journal

Dale Weinbaum, California Business Journal

Related Posts

Why you need health insurance
How Healthcare Companies Can Meet Regulatory Compliance
medical diagnose
How To Cope When Struggling To Get A Medical Diagnosis For Your Chronic Illness
2
ACCELERATING THE EARLY DRUG DISCOVERY PROCESS
advertisement
ADVERTISEMENT

CBJ Newsletter

Facebook Twitter LinkedIn Instagram LinkedIn

Advertise With CBJ

Contact Rick@CalBizJournal.com

CBJ Rates and Demographics

Job Postings

CEO Wanted


Requirements: BS/BA + 2yrs of Business Managing Experience

Mail Resume: Grand Life, Inc. 14647 Northam St. La Mirada, CA 90638.

$114,754/year

ADVERTISEMENT
1REALTOUR-SAN DIEGO-WEB DESIGN
Facebook Twitter LinkedIn LinkedIn Instagram
C B J   LOGO  SVG-01
  • About
  • Contact California Business Journal
  • Testimonials
  • Demographics & Advertising Rates
  • Terms & Conditions

Categories

  • Art & Culture
  • Business
  • California Hotel Listings
  • Daily Updates
  • Editor's Choice
  • Education
  • Featured
  • Finance
  • Food & Dining
  • Health & Fitness
  • Human Interest
  • Insurance
  • Law
  • Lawyers
  • Marketing
  • Medical
  • News
  • Newsletter
  • Opinion
  • People
  • Popular
  • Real Estate
  • Social Media
  • Technology
  • Uncategorized

CBJ Partner Firebrand Media

Laguna Beach Independent Newspaper
 Laguna Beach City Guide
 Newport Beach Independent Newspaper
Newport Beach Country Club Magazine
  Montage Magazine
 Omni Escapes Hotel Magazine
 Bespoke Concierge New York
 Evans Hotels
 Laguna Beach Magazine
 On The Menu Laguna Beach
 Newport Beach Magazine
Coastal Real Estate Guide (NB,LB, CDM)
Monarch Beach Resort Magazine
 Pacific Coast Magazine (SoCal)
Sea Island Life Magazine
Salamander Hotel & Resorts Magazine
 View our entire portfolio

 

Most Viewed

  • Gavel, scales of justice and law books

    Lawsuit Basics: How Much Does It Cost to Sue Someone?

    0 shares
    Share 0 Tweet 0
  • Investigation: Can TriumphFX Take Your Money?

    0 shares
    Share 0 Tweet 0
  • The Impact of Covid: Racing to Buy Second Citizenships

    3 shares
    Share 0 Tweet 0
  • What to Do When an Online Casino Refuses to Pay Out Your Winnings

    0 shares
    Share 0 Tweet 0
  • Top 5 Flavors On Elf Bar BC5000 Review

    0 shares
    Share 0 Tweet 0
  • NFL Paychecks: How Do NFL Players Get Paid?

    0 shares
    Share 0 Tweet 0
  • Five Reasons Why The Government Does Not Like Bitcoin

    0 shares
    Share 0 Tweet 0
  • How to Start a Telecommunication Business: A Step-By-Step Guide

    0 shares
    Share 0 Tweet 0
  • 6 Types of Business Records and Receipts Every Small Business Should Keep

    0 shares
    Share 0 Tweet 0
  • Temu’s New Shipping Policy Is A Smashing Hit For Shoppers All Over the Country

    0 shares
    Share 0 Tweet 0

Latest Articles

Q&A with Jennifer Woods, Vice President and Associate General Counsel of FrontDoor on Why Companies Should Release Sustainability Reports.

Q&A with Jennifer Woods, Vice President and Associate General Counsel of FrontDoor on Why Companies Should Release Sustainability Reports.

Best Practices for Establishing Secure Password Protocols

Best Practices for Establishing Secure Password Protocols

How to Up Your Marketing Game with Real Estate 3D Rendering

How to Up Your Marketing Game with Real Estate 3D Rendering

Tips For Designing A Vinyl Banner For Your Business

Tips For Designing A Vinyl Banner For Your Business

15 Useful Animation Makers for Novice Entrepreneurs (2023)

15 Useful Animation Makers for Novice Entrepreneurs For 2023

What is FinTech?

What is FinTech?

IT Company Tips: How to Develop IoT Mobile App

IT Company Tips: How to Develop IoT Mobile App

Offline Marketing Strategies for Brand Visibility and Awareness

Offline Marketing Strategies for Brand Visibility and Awareness

Around the U.S.: Benefits of Getting a Loan From Hard Money Lending in Colorado

Around the U.S.: Benefits of Getting a Loan From Hard Money Lending in Colorado

6 Easy Ways to Win the Online Casino

6 Easy Ways to Win the Online Casino

California Business Journal | California Business News, California News Media, California business articles | Orange County, Los Angeles, San Diego, Inland Empire, Northern California, San Francisco | Huntington Beach CA 92649 | (949) 648-3815
ALL RIGHTS RESERVED BY CALIFORNIA BUSINESS JOURNAL.
Site Design by 1REALTOUR

No Result
View All Result
  • Front Page
  • Business
  • Finance
  • People
  • Featured
  • Opinion
  • Technology
  • Law
  • News
  • Food
  • Art & Culture
  • Human Interest
  • Education
  • Insurance
  • Real Estate
  • Health & Fitness

California Business Journal | California Business News, California News Media, California business articles | Orange County, Los Angeles, San Diego, Inland Empire, Northern California, San Francisco | Huntington Beach CA 92649 | (949) 648-3815
ALL RIGHTS RESERVED BY CALIFORNIA BUSINESS JOURNAL.
Site Design by 1REALTOUR